Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 0.958


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NCOR1chr17_-_159144850.693.4e-03Click!
DMAP1chr1_+_44451698-0.401.3e-01Click!
SMARCA5chr4_+_1446540050.283.0e-01Click!
SMARCC2chr12_-_548695680.107.0e-01Click!
NCOR2chr12_-_123617962-0.107.2e-01Click!
SMARCA1chrX_-_128485062-0.087.7e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_13018123 1.591 NM_001164271
DLC1
deleted in liver cancer 1
chr10_+_17312654 1.111 VIM
vimentin
chr14_+_36196523 1.105 NM_006194
PAX9
paired box 9
chr9_-_23816062 0.992 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_+_11694172 0.965 ETV6
ets variant 6
chr9_-_21340885 0.921 NM_021002
IFNA6
interferon, alpha 6
chr2_-_55090759 0.910 NM_007008
RTN4
reticulon 4
chr14_+_74299748 0.909 NM_019589
YLPM1
YLP motif containing 1
chr4_-_39199527 0.903 UGDH
UDP-glucose 6-dehydrogenase
chr6_-_138862271 0.875 NM_001144060
NHSL1
NHS-like 1
chr10_+_28918672 0.869 WAC
WW domain containing adaptor with coiled-coil
chr14_+_99601498 0.833 NM_016337
EVL
Enah/Vasp-like
chr9_-_21192201 0.813 NM_021057
IFNA7
interferon, alpha 7
chr6_-_138862273 0.764


chr2_+_228045053 0.760 AGFG1
ArfGAP with FG repeats 1
chr14_+_99601517 0.740 EVL
Enah/Vasp-like
chr2_+_228045121 0.735 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr18_+_29573152 0.699 ASXL3
additional sex combs like 3 (Drosophila)
chr10_+_102662675 0.693 FAM178A
family with sequence similarity 178, member A
chr9_-_21218132 0.686 NM_021268
IFNA17
interferon, alpha 17
chr10_-_102663070 0.676


chr11_-_128399218 0.660 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr18_-_49944986 0.637 MBD2
methyl-CpG binding domain protein 2
chr9_+_2707525 0.626 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr5_+_140235114 0.622 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr4_+_71330797 0.617 NM_001145006
MUC7
mucin 7, secreted
chr3_-_121117647 0.609 GSK3B
glycogen synthase kinase 3 beta
chr8_+_76614757 0.591 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr16_-_3783475 0.589 CREBBP
CREB binding protein
chr9_-_8723893 0.580 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr13_+_23042722 0.563 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr16_+_24475129 0.550 RBBP6
retinoblastoma binding protein 6
chr1_+_84402962 0.547 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_34700062 0.540 NM_002989
CCL21
chemokine (C-C motif) ligand 21
chr8_-_38324809 0.537 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr13_-_99422163 0.536 NM_033132
ZIC5
Zic family member 5 (odd-paired homolog, Drosophila)
chr14_-_106184988 0.519 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_66346417 0.513 NM_198283
EYS
eyes shut homolog (Drosophila)
chr10_+_103995248 0.508 GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr8_-_93099040 0.493 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_33319680 0.488 HIPK3
homeodomain interacting protein kinase 3
chr9_-_5997891 0.483 NM_001017969
KIAA2026
KIAA2026
chr11_+_109468734 0.482 ZC3H12C
zinc finger CCCH-type containing 12C
chr7_+_17349425 0.469 AHR
aryl hydrocarbon receptor
chr10_-_14412813 0.467 NM_018027
FRMD4A
FERM domain containing 4A
chr9_+_17124974 0.466 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr16_-_51139214 0.463 NM_001146188
TOX3
TOX high mobility group box family member 3
chr14_+_56927066 0.453 NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr15_+_42790951 0.452 NM_004048
B2M
beta-2-microglobulin
chr3_+_125586241 0.446 KALRN
kalirin, RhoGEF kinase
chr10_+_103995297 0.445 NM_004193
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr13_-_102517196 0.444 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr3_-_158704056 0.442 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr13_-_25687062 0.437 RNF6
ring finger protein (C3H2C3 type) 6
chr11_+_63412562 0.436 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr6_-_128263868 0.432 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr1_-_103346639 0.430 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr2_-_210726539 0.428 C2orf67
chromosome 2 open reading frame 67
chr1_-_103346482 0.427 COL11A1
collagen, type XI, alpha 1
chr12_+_16397617 0.425 NM_145764
MGST1
microsomal glutathione S-transferase 1
chr5_-_138753443 0.424 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr3_-_27473248 0.419 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr18_-_41923571 0.418 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr12_-_15757114 0.412 EPS8
epidermal growth factor receptor pathway substrate 8
chr2_-_215711313 0.409 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr13_+_48448912 0.406 FNDC3A
fibronectin type III domain containing 3A
chr2_+_166137091 0.405 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr16_+_54158084 0.401 NM_032330
CAPNS2
calpain, small subunit 2
chr9_+_21399132 0.401 NM_002170
IFNA8
interferon, alpha 8
chr11_+_113671744 0.396 NM_006169
NNMT
nicotinamide N-methyltransferase
chr3_+_123279439 0.395 NM_006889
CD86
CD86 molecule
chr12_+_14409875 0.389 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr15_-_42790805 0.387


chr10_-_123724698 0.386 NM_001167865
NM_017615
NSMCE4A

non-SMC element 4 homolog A (S. cerevisiae)

chr2_+_165858586 0.385 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr10_+_60607232 0.385 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr5_+_135496421 0.381 NM_001001419
NM_001001420
NM_005903
SMAD5


SMAD family member 5


chr13_+_48448950 0.379 FNDC3A
fibronectin type III domain containing 3A
chr14_-_24115268 0.377 NM_001911
CTSG
cathepsin G
chr20_-_34921689 0.377 NM_199181
KIAA0889
KIAA0889
chr5_+_92944680 0.377 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr14_-_88948486 0.377 FOXN3
forkhead box N3
chrX_+_78087484 0.376 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr11_-_88436463 0.375 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr14_+_75687997 0.370 NM_017926
NM_017972
C14orf118

chromosome 14 open reading frame 118

chr9_+_106371269 0.369 NM_001004483
OR13C8
olfactory receptor, family 13, subfamily C, member 8
chr1_+_938709 0.368 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr17_-_1195096 0.368 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr11_-_27637771 0.363 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr2_-_55053398 0.363


chr4_+_93444572 0.363 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr10_+_124135574 0.362 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr11_-_104421240 0.358 NM_001017534
NM_052889
CARD16

CASP1
caspase recruitment domain family, member 16

caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr11_+_91724909 0.357 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr20_+_30409649 0.350 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr21_-_30614477 0.349 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr14_+_20580224 0.347 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr1_-_118529303 0.347 NM_206996
SPAG17
sperm associated antigen 17
chr4_-_116254381 0.344 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr6_+_52159143 0.343 NM_002190
IL17A
interleukin 17A
chr5_-_101862447 0.342 NM_173488
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr20_-_23010786 0.341 CD93
CD93 molecule
chr3_+_63928459 0.340 NM_001128149
ATXN7
ataxin 7
chr8_-_114518194 0.339 NM_052900
NM_198123
CSMD3

CUB and Sushi multiple domains 3

chr10_+_102662315 0.339 NM_001136123
NM_018121
FAM178A

family with sequence similarity 178, member A

chr11_-_123261549 0.337 NM_001013743
TMEM225
transmembrane protein 225
chr6_-_123999640 0.332 NM_006073
TRDN
triadin
chr14_+_75688025 0.328 C14orf118
chromosome 14 open reading frame 118
chr4_-_140443061 0.328 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr3_+_101720753 0.327 TMEM45A
transmembrane protein 45A
chr9_+_124477135 0.326 NM_001005234
OR1L3
olfactory receptor, family 1, subfamily L, member 3
chr3_-_69381995 0.324 FRMD4B
FERM domain containing 4B
chr12_-_27126721 0.319 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr9_-_33015091 0.317 APTX
aprataxin
chr22_+_38652555 0.316 GRAP2
GRB2-related adaptor protein 2
chr20_+_13924263 0.313 MACROD2
MACRO domain containing 2
chr6_+_157140954 0.308 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr6_+_110608284 0.304 NM_015891
CDC40
cell division cycle 40 homolog (S. cerevisiae)
chr6_+_72653420 0.302 RIMS1
regulating synaptic membrane exocytosis 1
chr9_-_21472311 0.300 NM_176891
IFNE
interferon, epsilon
chr5_-_93102952 0.300 NM_153216
POU5F2
POU domain class 5, transcription factor 2
chr5_+_140286485 0.298 NM_018898
NM_031882
PCDHAC1

protocadherin alpha subfamily C, 1

chr15_-_87679010 0.296 NM_001126131
NM_002693
POLG

polymerase (DNA directed), gamma

chr9_-_27287106 0.294 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr16_+_14201687 0.291 MKL2
MKL/myocardin-like 2
chr9_+_33807213 0.290 UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr5_-_27074407 0.289 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr2_-_166358792 0.288 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_+_154449334 0.287 NM_001145287
OPRM1
opioid receptor, mu 1
chr6_-_48186868 0.287 C6orf138
chromosome 6 open reading frame 138
chr14_+_20226762 0.284 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr12_+_11693909 0.283 ETV6
ets variant 6
chr11_-_104477367 0.281 NM_001007232
CARD17
caspase recruitment domain family, member 17
chr14_-_20969706 0.274 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr10_-_123724631 0.273


chr10_+_91082218 0.272 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr10_-_123724251 0.272 NSMCE4A
non-SMC element 4 homolog A (S. cerevisiae)
chr5_+_179065282 0.271 CANX
calnexin
chr21_-_26345294 0.271


chr12_-_60872814 0.269 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr14_-_24173205 0.269 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr4_-_122304925 0.268 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr5_+_54491702 0.267 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr16_-_21078262 0.267 NM_017539
DNAH3
dynein, axonemal, heavy chain 3
chr6_+_72653369 0.267 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr15_-_87679046 0.267 POLG
polymerase (DNA directed), gamma
chr14_+_75688042 0.266 C14orf118
chromosome 14 open reading frame 118
chr11_+_55351270 0.266 NM_001004739
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr20_+_56900116 0.265 NM_001077488
GNAS
GNAS complex locus
chr5_+_115415061 0.265 NM_001195581
LOC644100
hypothetical LOC644100
chr3_-_123766113 0.265 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr14_+_20595820 0.264 NM_138331
RNASE8
ribonuclease, RNase A family, 8
chr17_+_45617676 0.262


chr14_+_56927014 0.262 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_-_166359016 0.262 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr2_+_65517316 0.262 FLJ16124
FLJ16124 protein
chr10_+_106103503 0.260 NM_001008723
CCDC147
coiled-coil domain containing 147
chr14_-_34252695 0.260 NM_021914
CFL2
cofilin 2 (muscle)
chr5_+_147238466 0.257 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr14_-_102500694 0.257 CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr3_-_158703821 0.254 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr22_+_39931231 0.254 NM_031488
L3MBTL2
l(3)mbt-like 2 (Drosophila)
chr11_+_64950402 0.252


chr4_-_174774368 0.252 NM_006792
MORF4
mortality factor 4
chr14_-_106270497 0.252 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_215951161 0.251 FN1
fibronectin 1
chr6_+_157140895 0.250


chr3_+_112934016 0.246 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_+_112743615 0.246 NM_005816
NM_198196
CD96

CD96 molecule

chr2_-_215955206 0.246 FN1
fibronectin 1
chr11_+_82545784 0.245 NM_015885
PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
chr14_+_20222575 0.243 ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr8_+_118032370 0.243 NM_001172813
NM_001172815
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr14_+_101345878 0.242 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr3_-_150952944 0.241 NM_016094
COMMD2
COMM domain containing 2
chr2_+_228064531 0.241 AGFG1
ArfGAP with FG repeats 1
chr11_+_129445136 0.240


chrX_+_123307812 0.239 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chrX_+_145698993 0.238 NM_001144064
CXorf51
chromosome X open reading frame 51
chr7_-_78920806 0.238 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_-_36418869 0.237 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr2_-_166358951 0.235 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr22_-_27787793 0.235 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr11_+_129444877 0.234 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr6_+_72653126 0.233 RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_87359088 0.232 NM_014043
CHMP2B
chromatin modifying protein 2B
chr20_+_2851852 0.231 NM_080841
PTPRA
protein tyrosine phosphatase, receptor type, A
chr1_+_227506751 0.231 NM_006542
SPHAR
S-phase response (cyclin related)
chr20_-_29360048 0.231 NM_001037731
DEFB116
defensin, beta 116
chr13_+_27610379 0.231 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr18_-_38949481 0.230 NM_002930
RIT2
Ras-like without CAAX 2
chr3_+_50101428 0.229 RBM5
RNA binding motif protein 5
chr3_+_88281582 0.229 NM_173824
C3orf38
chromosome 3 open reading frame 38
chr10_-_98315090 0.229 TM9SF3
transmembrane 9 superfamily member 3
chr6_-_46811388 0.228 NM_001168357
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr1_+_157441824 0.227 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_-_156816312 0.227 NM_001004477
OR10X1
olfactory receptor, family 10, subfamily X, member 1
chr3_+_190831909 0.226 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr19_-_18246166 0.226 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr11_-_49960646 0.226 NM_001005270
OR4C12
olfactory receptor, family 4, subfamily C, member 12

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 7.64e-04 GO:0032501 multicellular organismal process
1.66 1.55e-03 GO:0051704 multi-organism process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 3.74e-02 GO:0071944 cell periphery

Nothing significant found in function category.